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Article

Galectin-3 in Inflammasome Activation and Primary Biliary Cholangitis Development.

International journal of molecular sciences - 19 Jul 2020

Arsenijevic Aleksandar, Stojanovic Bojana, Milovanovic Jelena, Arsenijevic Dragana, Arsenijevic Nebojsa, Milovanovic Marija

Abstract excerpt

Primary biliary cholangitis (PBC) is a chronic inflammatory autoimmune liver disease characterized by inflammation and damage of small bile ducts. The NLRP3 inflammasome is a multimeric complex of proteins that after activation with various stimuli initiates an inflammatory process. Increasing data obtained from animal studies implicate the role of NLRP3 inflammasome in the pathogenesis of various diseases....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32707678
DOI: 10.3390/ijms21145097
PMCID: PMC7404314

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