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Article

Juvenile generalized pustular psoriasis with IL36RN mutation treated with short-term infliximab.

Dermatologic therapy - 1 May 2016

Pan Junwei, Qiu Li, Xiao Ting, Chen Hong-Duo

Abstract excerpt

A 8-year-old Chinese boy with generalized pustular psoriasis (GPP) refractory to cyclosporine and methylprednisolone was treated successfully with two infusions of infliximab 3.3 mg/kg. He remained in remission for 21 months. Direct sequencing of IL36RN gene showed a homozygous mutation, c.115 + 6T>C. Juvenile GPP is a rare severe form of psoriasis occasionally associated with life-threatening complications. Like...

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Identifiers

PMID: 26627198
DOI: 10.1111/dth.12325

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CRP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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