Article
Clinical profile of patients with acute generalized pustular psoriasis with and without IL36RN mutations in multi-ethnic Johor Bahru, Malaysia.
Experimental dermatology - 1 Aug 2023
Choon Siew Eng, Tok Peter Seah Keng, Wong Kit Wan, Lim Yee Ting, Nanu Nalini M, Barker Jonathan N, Capon Francesca
Abstract excerpt
Generalized Pustular psoriasis (GPP), a rare and potentially life-threatening auto-inflammatory disease, is associated with IL36RN mutations. Here, we analyse the prevalence of IL36RN mutations in our multi-ethnic GPP cohort and assess differences in the clinical profile of patients with (IL36RN-positive) and without (IL36RN-negative) mutations. IL36RN mutations were present in 17.7% of 137 GPP patients (29.7% of...
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