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Article

Association of IL36RN mutations with clinical features, therapeutic response to acitretin, and frequency of recurrence in patients with generalized pustular psoriasis.

European journal of dermatology : EJD - 1 Apr 2018

Zhu Teng, Jin Hongzhong, Shu Dan, Li Feng, Wu Chao

Abstract excerpt

Previous studies have revealed that IL36RN mutations play a pivotal role in the pathogenesis of generalized pustular psoriasis (GPP), however, the clinical relevance is unclear. To investigate the correlation between IL36RN mutations and clinical features, recurrence frequency, and therapeutic response to acitretin in GPP patients with long-term follow-up. This retrospective cohort study, lasting 2-4 years,...

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PMID: 29619998
DOI: 10.1684/ejd.2018.3245

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