Article
Generalized pustular psoriasis in a toddler with IL36RN mutation: a case report.
Frontiers in immunology - 1 Jan 2024
Adi Ghaith, Shaath Mohammed Rami, Adi Kareem, Obaid Zaki, Aldosari Egab, AlKateb Faten Ahmed
Abstract excerpt
Generalized Pustular Psoriasis (GPP) is a dermatological autoinflammatory disease that rarely occurs in children and is associated with complex genetic factors. GPP pathogenesis has been associated with mutations in IL36RN gene, which encodes an interleukin-36 receptor antagonist. GPP usually occurs without a history of psoriasis in the patients or their family members. This case report describes the clinical...
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