Article
The response of aged mice to primary infection and re-infection with pneumonia virus of mice depends on their genetic background.
Immunobiology - 1 Mar 2016
Shrivastava Pratima, Watkiss Ellen, van Drunen Littel-van den Hurk Sylvia
Abstract excerpt
The pneumonia virus of mice (PVM) model is used to study respiratory syncytial virus (RSV) pathogenesis. The outcome of PVM infection varies in different inbred mouse strains, BALB/c being highly susceptible and C57BL/6 more resistant. As the disease symptoms induced by RSV infection can become more severe as people age, we examined the primary and secondary immune responses to infection with PVM in aged BALB/c...
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