Article
Early-life viral infection and allergen exposure interact to induce an asthmatic phenotype in mice.
Respiratory research - 3 Feb 2010
Siegle Jessica S, Hansbro Nicole, Herbert Cristan, Rosenberg Helene F, Domachowske Joseph B, Asquith Kelly L, Foster Paul S, Kumar Rakesh K
Abstract excerpt
BACKGROUND: Early-life respiratory viral infections, notably with respiratory syncytial virus (RSV), increase the risk of subsequent development of childhood asthma. The purpose of this study was to assess whether early-life infection with a species-specific model of RSV and subsequent allergen e...
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