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Article

SAGA DUB-Ubp8 Deubiquitylates Centromeric Histone Variant Cse4.

G3 (Bethesda, Md.) - 27 Nov 2015

Canzonetta Claudia, Vernarecci Stefano, Iuliani Michele, Marracino Cristina, Belloni Claudia, Ballario Paola, Filetici Patrizia

Abstract excerpt

Aneuploidy, the unbalanced segregation of chromosomes during cell division, is recurrent in many tumors and the cause of birth defects and genetic diseases. Centromeric chromatin represents the chromosome attachment site to the mitotic spindle, marked by specialized nucleosomes containing a specific histone variant, CEN-H3/Cse4, in yeast. Mislocalization of Cse4 outside the centromere is deleterious and may cause...

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Share to Centromere
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26613948
DOI: 10.1534/g3.115.024877
PMCID: PMC4751549

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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