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Article

Longitudinal three-dimensional visualisation of autoimmune diabetes by functional optical coherence imaging.

Diabetologia - 1 Mar 2016

Berclaz Corinne, Schmidt-Christensen Anja, Szlag Daniel, Extermann Jerome, Hansen Lisbeth, Bouwens Arno, Villiger Martin, Goulley Joan, Schuit Frans, Grapin-Botton Anne, Lasser Theo, Holmberg Dan

Abstract excerpt

AIMS/HYPOTHESIS: It is generally accepted that structural and functional quantitative imaging of individual islets would be beneficial to elucidate the pathogenesis of type 1 diabetes. We here introduce functional optical coherence imaging (FOCI) for fast, label-free monitoring of beta cell destruction and associated alterations of islet vascularisation. METHODS: NOD mouse and human islets transplanted into the...

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PMID: 26613896
DOI: 10.1007/s00125-015-3819-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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