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Article

A novel technique for the in vivo imaging of autoimmune diabetes development in the pancreas by two-photon microscopy.

PloS one - 23 Dec 2010

Coppieters Ken, Martinic Marianne M, Kiosses William B, Amirian Natalie, von Herrath Matthias

Abstract excerpt

Type 1 diabetes (T1D) is characterized by the immune-mediated destruction of beta cells in the pancreas. Little is known about the in vivo dynamic interactions between T cells and beta cells or the kinetic behavior of other immune cell subsets in the pancreatic islets. Utilizing multiphoton microscopy we have designed a technique that allows for the real-time visualization of diabetogenic T cells and dendritic...

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Identifiers

PMID: 21203413
DOI: 10.1371/journal.pone.0015732
PMCID: PMC3009738

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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