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Nonlinear Imaging Detection of Organ Fibrosis in Minute Samples for Early Stage Utilizing Dual-Channel Two-Photon Excitation

2025-04-30

Abstract excerpt

Histopathological staining remains the fibrosis diagnostic gold standard yet suffers from staining artifacts and variability. Although nonlinear optical techniques (e.g., spontaneous fluorescence, Second Harmonic Generation) enhance accuracy but struggle with rapid trace-level detection of fibrosis. To address these limitations, a dual-channel nonlinear optical imaging system with excitation wavelengths at 780 nm...

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Literature Corpus work
ebce3825-5322-569e-8742-4b21c5d38be0
DOI
10.20944/preprints202504.2489.v1
Open publication

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Nonlinear Imaging Detection of Organ Fibrosis in Minute Samples for Early Stage Utilizing Dual-Channel Two-Photon ExcitationDOI 10.20944/preprints202504.2489.v1
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