Article
In vivo Ca2+ dynamics in single pancreatic β cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Jan 2020
Jacob Stefan, Köhler Martin, Tröster Philip, Visa Montse, García-Prieto Concha F, Alanentalo Tomas, Moede Tilo, Leibiger Barbara, Leibiger Ingo B, Berggren Per-Olof
Abstract excerpt
The dynamics of cytoplasmic free Ca2+ concentration ([Ca2+]i) in pancreatic β cells is central to our understanding of β-cell physiology and pathology. In this context, there are numerous in vitro studies available but existing in vivo data are scarce. We now critically evaluate the anterior chamber of the eye as an in vivo, non-invasive, imaging site for measuring [Ca2+]i dynamics longitudinally in three...
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