Article
Dominance from the perspective of gene-gene and gene-chemical interactions.
Genetica - 1 Feb 2016
Gladki Arkadiusz, Zielenkiewicz Piotr, Kaczanowski Szymon
Abstract excerpt
In this study, we used genetic interaction (GI) and gene-chemical interaction (GCI) data to compare mutations with different dominance phenotypes. Our analysis focused primarily on Saccharomyces cerevisiae, where haploinsufficient genes (HI; genes with dominant loss-of-function mutations) were found to be participating in gene expression processes, namely, the translation and regulation of gene transcription....
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