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Article

Exploring the etiology of haploinsufficiency.

BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Feb 2002

Veitia Reiner A

Abstract excerpt

The focus of this essay is the phenomenon of haploinsufficiency (HI), a manifestation of genetic dominance that arises when only one allele of a normally diploid locus is present. Specifically, I examine the nature of HI for transcription factor genes. Although the concept of HI applies to many such genes, there is a potentially large variety of mechanisms that underlie it. Even when the phenomenon is linked in...

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PMID: 11835282
DOI: 10.1002/bies.10023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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