Article
Autism-related behavioral phenotypes in an inbred rat substrain.
Behavioural brain research - 1 Aug 2014
Zhang-James Yanli, Yang Li, Middleton Frank A, Yang Lina, Patak Jameson, Faraone Stephen V
Abstract excerpt
Behavioral and genetic differences among Wistar-Kyoto (WKY) rats from different vendors and different breeders have long been observed, but generally overlooked. In our prior work, we found that two closely related WKY substrains, the WKY/NCrl and WKY/NHsd rats, differ in a small percentage of their genome which appeared to be highly enriched for autism risk genes. Although both substrains have been used widely...
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