Article
Genetic analysis of genes causing hypertension and stroke in spontaneously hypertensive rats.
International journal of molecular medicine - 1 May 2013
Yamamoto Hideyuki, Okuzaki Daisuke, Yamanishi Kyosuke, Xu Yunfeng, Watanabe Yuko, Yoshida Momoko, Yamashita Akifumi, Goto Naohisa, Nishiguchi Seiji, Shimada Kazunori, Nojima Hiroshi, Yasunaga Teruo, Okamura Haruki, Matsunaga Hisato, Yamanishi Hiromichi
Abstract excerpt
Spontaneously hypertensive rats (SHR) and stroke-prone SHR (SHRSP) are frequently used as model rats not only in studies of essential hypertension and stroke, but also in studies of attention deficit hyperactivity disorder (ADHD). Normotensive Wistar-Kyoto rats (WKY) are normally used as controls in these studies. In this study, using these rats, we aimed to identify the genes causing hypertension and stroke, as...
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