Article
N-methyl-D-aspartate receptor subunit dysfunction at hippocampal glutamatergic synapses in an animal model of attention-deficit/hyperactivity disorder.
Neuroscience - 12 Jan 2009
Jensen V, Rinholm J E, Johansen T J, Medin T, Storm-Mathisen J, Sagvolden T, Hvalby O, Bergersen L H
Abstract excerpt
Attention-deficit/hyperactivity disorder (ADHD) is the most common neurobehavioural disorder among children. ADHD children are hyperactive, impulsive and have problems with sustained attention. These cardinal features are also present in the best validated animal model of ADHD, the spontaneously hypertensive rat (SHR), which is derived from the Wistar Kyoto rat (WKY). Current theories of ADHD relate symptom...
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