Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Relationship between three serotonin receptor subtypes (HTR3A, HTR2A and HTR4) and treatment-resistant schizophrenia in the Japanese population.

Neuroscience letters - 18 Apr 2008

Ji Xiaofei, Takahashi Nagahide, Saito Shinichi, Ishihara Ryoko, Maeno Nobuhisa, Inada Toshiya, Ozaki Norio

Abstract excerpt

The proportion of treatment-resistant schizophrenia (TRS) has been estimated as 20-40% in the schizophrenic patients. Genetic factors are considered to be involved in the development of this condition. Serotonin subtypes are hypothesized to be the candidate genes. In the present study, single marker and haplotype analyses between several mutations of serotonin receptor subtypes (HTR2A, HTR3A and HTR4) and TRS...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antipsychotic Agents
Share to Drug Resistance

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Pharmacogenetics

Share to Receptor, Serotonin, 5-HT2A

Share to Receptors, Serotonin

Share to Receptors, Serotonin, 5-HT3

Share to Schizophrenia

Source

Identifiers

PMID: 18359159
DOI: 10.1016/j.neulet.2008.01.083

Genes

HTR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Relationship between three serotonin receptor subtypes (HTR3A, HTR2A and HTR4) and treatment-resistant schizophrenia in the Japanese population.PMID 18359159Read ↗

An association between serotonin receptor 3B gene (HTR3B) and treatment-resistant schizophrenia (TRS) in a Japanese population.Semantic proximity Read ↗

Effect of serotonin-related gene polymorphisms on pathogenesis and treatment response in Korean schizophrenic patients.Semantic proximity Read ↗

Investigating DRD2 and HTR2A polymorphisms in treatment-resistant schizophrenia: a comparative analysis with other treatment-resistant mental disorders and the healthy state.Semantic proximity Read ↗

The contribution of the 5-hydroxytryptamine receptor 2 A gene polymorphisms rs6311 and rs6313 to Schizophrenia in Iran.Semantic proximity Read ↗

Serotonin transporter functional polymorphisms potentially increase risk of schizophrenia separately and as a haplotype.Semantic proximity Read ↗

Associations of serotonin receptor gene HTR3A, HTR3B, and HTR3A haplotypes with bipolar disorder in Chinese patients.Semantic proximity Read ↗

Association evaluation of 5-HTR2A manifested salient contribution of rs6311 and rs6313 in increasing the occurrence of schizophreniaSemantic proximity Read ↗

HTR2A is associated with SSRI response in major depressive disorder in a Japanese cohort.Semantic proximity Read ↗

Association between a polymorphism of the HTR3A gene and therapeutic response to risperidone treatment in drug-naive Chinese schizophrenia patients.Semantic proximity Read ↗

Serotonin 7 Receptor Variants Are Not Associated with Response to Second-Generation Antipsychotics in Japanese Schizophrenia Patients.Semantic proximity Read ↗

Association of serotonin 2A receptor and lack of association of CYP1A2 gene polymorphism with tardive dyskinesia in a Turkish population.Semantic proximity Read ↗

Pharmacogenetics analysis of serotonin receptor gene variants and clinical response to risperidone in Han Chinese schizophrenic patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.