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Article

HTR1A Gene Polymorphisms and 5-HT1A Receptor Partial Agonist Antipsychotics Efficacy in Schizophrenia.

Journal of clinical psychopharmacology - 1 Jun 2015

Takekita Yoshiteru, Fabbri Chiara, Kato Masaki, Nonen Shinpei, Sakai Shiho, Sunada Naotaka, Koshikawa Yosuke, Wakeno Masataka, Okugawa Gaku, Kinoshita Toshihiko, Serretti Alessandro

Abstract excerpt

Individual differences in serotonin 1A (5-HT1A) receptor may result in variable response to antipsychotics with 5-HT1A receptor partial agonism. We investigated the relationship between 5-HT1A receptor gene (HTR1A) single nucleotide polymorphisms (SNPs) and efficacy of antipsychotics with 5-HT1A receptor partial agonism in Japanese patients with schizophrenia. Perospirone or aripiprazole was administered to 100...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25822479
DOI: 10.1097/JCP.0000000000000304

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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