Article
Relationship between genetic polymorphisms in the HTR1A gene and paranoid schizophrenia in a northern Han Chinese population.
Journal of molecular neuroscience : MN - 1 Mar 2013
Zhou Xue, Ding Mei, Ding Chunli, Yao Jun, Pang Hao, Xing Jiaxin, Xuan Jinfeng, Wang Baojie
Abstract excerpt
The hypothesis for the etiology of schizophrenia involves various neurotransmitters, including 5-HT. Metabolic disorder of 5-HT is an important underlying neurobiochemical cause leading to the development of mental illness. Abnormality in the receptors involved in 5-HT synthesis and metabolism may affect the functioning of 5-HT in the central nervous system. There are seven types of 5-HT receptor families, with a...
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