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Article

A valveless rotary microfluidic device for multiplex point mutation identification based on ligation-rolling circle amplification.

Biosensors & bioelectronics - 15 Apr 2016

Heo Hyun Young, Chung Soyi, Kim Yong Tae, Kim Do Hyun, Seo Tae Seok

Abstract excerpt

Genetic variations such as single nucleotide polymorphism (SNP) and point mutations are important biomarkers to monitor disease prognosis and diagnosis. In this study, we developed a novel rotary microfluidic device which can perform multiplex SNP typing on the mutation sites of TP53 genes. The microdevice consists of three glass layers: a channel wafer, a Ti/Pt electrode-patterned resistance temperature detector...

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Identifiers

PMID: 26606304
DOI: 10.1016/j.bios.2015.11.039

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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