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Article

MicroRNA-145 Suppresses Osteosarcoma Metastasis via Targeting MMP16

1 Jan 2015

Abstract excerpt

BACKGROUND: Metastasis is a leading cause of mortality for osteosarcoma (OS) patients, and its molecular pathological mechanisms remain to be elucidated. Previous studies have suggested a significant role of microRNAs (miRNAs) in the control of cancel cell migration and invasion. METHODS: Real-time PCR was used to screen the differentially expressed miRNAs between OS with or without metastasis, and miR-145...

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PMID: 26605780
DOI: 10.1159/000438575

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