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Article

MicroRNA-138 functions as a tumor suppressor in osteosarcoma by targeting differentiated embryonic chondrocyte gene 2

19 Apr 2016

Abstract excerpt

BACKGROUND: MicroRNA-138 (miR-138) has been proven to be a tumor suppressor gene in various types of tumors. However, the expression and the role of miR-138 in human osteosarcoma are still poorly understood. We investigated the function and the underlying mechanism of miR-138 in osteosarcoma. METHODS: The expression of miR-138 in human osteosarcoma tissues and cell lines was detected by real-time PCR analysis....

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PMID: 27095063
DOI: 10.1186/s13046-016-0348-5

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