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Article

miR-216a inhibits osteosarcoma cell proliferation, invasion and metastasis by targeting CDK14

12 Oct 2017

Abstract excerpt

Osteosarcoma (OS) has emerged as the most common primary musculoskeletal malignant tumour affecting children and young adults. Cyclin-dependent kinases (CDKs) are closely associated with gene regulation in tumour biology. Accumulating evidence indicates that the aberrant function of CDK14 is involved in a broad spectrum of diseases and is associated with clinical outcomes. MicroRNAs (miRNAs) are crucial...

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PMID: 29022909
DOI: 10.1038/cddis.2017.499

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