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miR‐454 is down‐regulated in osteosarcomas and suppresses cell proliferation and invasion by directly targeting c‐Met

16 Apr 2015

Abstract excerpt

OBJECTIVES: Osteosarcoma is the most common primary bone malignancy of children and young adults. Increasing evidence has shown that microRNAs (miRNAs) are associated with cancer development, but, little is known concerning the role of miR-454 in osteosarcoma. MATERIALS AND METHODS: qRT-PCR was performed to detect expression of miR-454 in osteosarcoma cell lines and tissues. To understand its role in...

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PMID: 25880599
DOI: 10.1111/cpr.12187

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