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Article

The Epigenetic Regulation of SOX9 by miR‐145 in Human Chondrosarcoma

21 Aug 2014

Abstract excerpt

Chondrosarcoma is the most common primary bone malignancy in the adult population with a high rate of pulmonary metastasis. Chondrosarcoma is managed with surgical excision as the tumors do not respond well to conventional chemotherapy or radiation therapy. Thus, there exists a dire need to develop systemic treatment options to target chondrosarcoma cells for metastatic spread. We hypothesized that the expression...

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PMID: 25145279
DOI: 10.1002/jcb.24940

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