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Article

A multicentric association study between 39 genes and nonsyndromic cleft lip and palate in a Brazilian population.

Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery - 1 Jan 2016

de Araujo Tânia Kawasaki, Secolin Rodrigo, Félix Têmis Maria, de Souza Liliane Todeschini, Fontes Marshall Ítalo Barros, Monlleó Isabella Lopes, de Souza Josiane, Fett-Conte Agnes Cristina, Ribeiro Erlane Marques, Xavier Ana Carolina, de Rezende Adriana Augusto, Simioni Milena, Ribeiro-dos-Santos Ândrea Kely Campos, dos Santos Sidney Emanuel Batista, Gil-da-Silva-Lopes Vera Lúcia

Abstract excerpt

PURPOSE: The aim of this study was to use the TaqMan OpenArray system to evaluate associations between 39 genes and the etiology of nonsyndromic cleft lip and palate (NSCLP) in a Brazilian population. MATERIAL AND METHODS: This case-control association study was designed with 80.11% statistical power according to logistic regression (GPOWER software). The case group had 182 patients with NSCLP enrolled in the...

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Source

Identifiers

PMID: 26602496
DOI: 10.1016/j.jcms.2015.07.026

Genes

KIF7
AXIN2
BMP4
DVL2
JAG2
MSX1
MSX2
PAX9
PRSS35
SHH
SPRY1
TBX10
VAX1
WNT11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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