Article
Genome-wide association study identifies two susceptibility loci for nonsyndromic cleft lip with or without cleft palate.
Nature genetics - 1 Jan 2010
Mangold Elisabeth, Ludwig Kerstin U, Birnbaum Stefanie, Baluardo Carlotta, Ferrian Melissa, Herms Stefan, Reutter Heiko, de Assis Nilma Almeida, Chawa Taofik Al, Mattheisen Manuel, Steffens Michael, Barth Sandra, Kluck Nadine, Paul Anna, Becker Jessica, Lauster Carola, Schmidt Gül, Braumann Bert, Scheer Martin, Reich Rudolf H, Hemprich Alexander, Pötzsch Simone, Blaumeiser Bettina, Moebus Susanne, Krawczak Michael, Schreiber Stefan, Meitinger Thomas, Wichmann Hans-Erich, Steegers-Theunissen Regine P, Kramer Franz-Josef, Cichon Sven, Propping Peter, Wienker Thomas F, Knapp Michael, Rubini Michele, Mossey Peter A, Hoffmann Per, Nöthen Markus M
Abstract excerpt
We conducted a genome-wide association study for nonsyndromic cleft lip with or without cleft palate (NSCL/P) in 401 affected individuals and 1,323 controls, with replication in an independent sample of 793 NSCL/P triads. We report two new loci associated with NSCL/P at 17q22 (rs227731, combined...
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