Article
Genetic variants of 20q12 contributed to non-syndromic orofacial clefts susceptibility.
Oral diseases - 1 Jan 2017
Yin X, Ma L, Li Y, Xu M, Wang W, Wang H, Yuan H, Du Y, Li S, Ma J, Jiang H, Wang L, Zhang W, Pan Y
Abstract excerpt
OBJECTIVE: Previous genomewide association studies (GWAS) identified a region near MAFB at chr20q12 associated with non-syndromic orofacial clefts (NSOC) susceptibility. However, whether other SNPs in this area could independently contribute to non-syndromic orofacial clefts in Chinese populations remained obscure. MATERIALS AND METHODS: We selected 24 SNPs based on a haplotype-tagging SNP strategy and evaluated...
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