Article
Analysis of susceptibility polymorphisms for nonsyndromic cleft lip with or without cleft palate in the Brazilian population.
Birth defects research. Part A, Clinical and molecular teratology - 1 Jan 2014
de Aquino Sibele Nascimento, Messetti Ana Camila, Hoshi Ryuchi, Borges Andréa, Viena Camila Sane, Reis Sílvia R A, Oliveira Swerts Mário Sérgio, Graner Edgard, Martelli-Júnior Hercílio, Coletta Ricardo D
Abstract excerpt
BACKGROUND: Although genome-wide association studies have identified several susceptibility loci for nonsyndromic cleft lip with or without cleft palate (NSCL/P) in populations around the world, the role of most loci is unknown in the highly heterogeneous Brazilian population. METHODS: To determine the association of 7 markers that showed genome-wide significant association in Brazilians with NSCL/P, we conducted...
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