Article
Nuclear genomic control of naturally occurring variation in mitochondrial function in Drosophila melanogaster.
BMC genomics - 22 Nov 2012
Jumbo-Lucioni Patricia, Bu Su, Harbison Susan T, Slaughter Juanita C, Mackay Trudy F C, Moellering Douglas R, De Luca Maria
Abstract excerpt
BACKGROUND: Mitochondria are organelles found in nearly all eukaryotic cells that play a crucial role in cellular survival and function. Mitochondrial function is under the control of nuclear and mitochondrial genomes. While the latter has been the focus of most genetic research, we remain largely ignorant about the nuclear-encoded genomic control of inter-individual variability in mitochondrial function. Here,...
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