Article
Empirical fitness models for hepatitis C virus immunogen design.
Physical biology - 24 Nov 2015
Hart Gregory R, Ferguson Andrew L
Abstract excerpt
UNLABELLED: Hepatitis C virus (HCV) afflicts 170 million people worldwide, 2%-3% of the global population, and kills 350 000 each year. Prophylactic vaccination offers the most realistic and cost effective hope of controlling this epidemic in the developing world where expensive drug therapies are not available. Despite 20 years of research, the high mutability of the virus and lack of knowledge of what...
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