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Article

Increased Notch Signaling Enhances Radioresistance of Malignant Stromal Cells Induced by Glioma Stem/ Progenitor Cells.

PloS one - 1 Jan 2015

Shen Yuntian, Chen Hua, Zhang Jinshi, Chen Yanming, Wang Mengyao, Ma Jiawei, Hong Lei, Liu Ning, Fan Qiuhong, Lu Xueguan, Tian Ye, Wang Aidong, Dong Jun, Lan Qing, Huang Qiang

Abstract excerpt

BACKGROUND: Host malignant stromal cells induced by glioma stem/progenitor cells were revealed to be more radiation-resistant than the glioma stem/progenitor cells themselves after malignant transformation in nude mice. However, the mechanism underlying this phenomenon remains unclear. METHODS: Malignant stromal cells induced by glioma stem/progenitor cell 2 (GSC-induced host brain tumor cells, ihBTC2) were...

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Source

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Identifiers

PMID: 26599017
DOI: 10.1371/journal.pone.0142594
PMCID: PMC4657951

Genes

GSC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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