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Article

Resveratrol, a potential radiation sensitizer for glioma stem cells both in vitro and in vivo

10 Nov 2015

Abstract excerpt

Glioblastoma is a malignant human cancer that confers a dismal prognosis. Ionizing radiation (IR) is applied as the standard treatment for malignant gliomas. However, radiotherapy remains merely palliative because of the existence of glioma stem cells (GSCs), which are regarded as highly radioresistant "seed" cells. In this study, the effect and possible mechanisms of radiotherapy in combination with resveratrol...

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PMID: 26698406
DOI: 10.1016/j.jphs.2015.11.001

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