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Cancer Stem Cells and Radioresistance: DNA Repair and Beyond

21 Jun 2019

Abstract excerpt

The current preclinical and clinical findings demonstrate that, in addition to the conventional clinical and pathological indicators that have a prognostic value in radiation oncology, the number of cancer stem cells (CSCs) and their inherent radioresistance are important parameters for local control after radiotherapy. In this review, we discuss the molecular mechanisms of CSC radioresistance attributable to DNA...

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PMID: 31234336
DOI: 10.3390/cancers11060862

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