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Targeting glioma stem cells: A novel framework for brain tumors

16 Aug 2011

Abstract excerpt

The past decade has seen a dramatic increase in stem cell research that focuses on glioma stem cells (GSC) and their mechanisms of action, revealing multiple potential targets for primary malignant brain tumors. Herein, we present a novel framework for considering GSC targets based on direct and indirect strategies. Direct strategies target GSC molecular pathways to overcome their resistance to radiation and...

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PMID: 21848914
DOI: 10.1111/j.1349-7006.2011.02064.x

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