Article
Pemphigus vulgaris: recent advances in our understanding of its pathogenesis.
Minerva stomatologica - 1 Apr 2007
Femiano F
Abstract excerpt
Pemphigus, a group of bullous diseases affecting the oral mucosa and the skin, is caused by antibody-mediated autoimmune reaction to desmogleins (Dsg), desmosomal transmembrane glycoproteins, leading to acantholysis. Pemphigus is classified into pemphigus vulgaris (PV), with suprabasal acantholysis, and pemphigus foliaceus (PF), with acantholysis in the more superficial epidermis. Pemphigus vulgaris is...
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