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Article

Epistatic Interactions in the Arabinose Cis-Regulatory Element.

Molecular biology and evolution - 1 Mar 2016

Lagator Mato, Igler Claudia, Moreno Anaísa B, Guet Călin C, Bollback Jonathan P

Abstract excerpt

Changes in gene expression are an important mode of evolution; however, the proximate mechanism of these changes is poorly understood. In particular, little is known about the effects of mutations within cis binding sites for transcription factors, or the nature of epistatic interactions between these mutations. Here, we tested the effects of single and double mutants in two cis binding sites involved in the...

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Identifiers

PMID: 26589997
DOI: 10.1093/molbev/msv269
PMCID: PMC4760080

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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