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Article

Analysis of epistatic interactions and fitness landscapes using a new geometric approach.

BMC evolutionary biology - 13 Apr 2007

Beerenwinkel Niko, Pachter Lior, Sturmfels Bernd, Elena Santiago F, Lenski Richard E

Abstract excerpt

BACKGROUND: Understanding interactions between mutations and how they affect fitness is a central problem in evolutionary biology that bears on such fundamental issues as the structure of fitness landscapes and the evolution of sex. To date, analyses of fitness landscapes have focused either on the overall directional curvature of the fitness landscape or on the distribution of pairwise interactions. In this...

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Identifiers

PMID: 17433106
DOI: 10.1186/1471-2148-7-60
PMCID: PMC1865543

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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