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The RS685012 Polymorphism of ACCN2, the Human Ortholog of Murine Acid-Sensing Ion Channel (ASIC1) Gene, is Highly Represented in Patients with Panic Disorder.

Neuromolecular medicine - 1 Mar 2016

Gugliandolo Agnese, Gangemi Chiara, Caccamo Daniela, Currò Monica, Pandolfo Gianluca, Quattrone Diego, Crucitti Manuela, Zoccali Rocco Antonio, Bruno Antonio, Muscatello Maria Rosaria Anna

Abstract excerpt

Panic disorder (PD) is a disabling anxiety disorder that is characterized by unexpected, recurrent panic attacks, associated with fear of dying and worrying about possible future attacks or other behavioral changes as a consequence of the attacks. The acid-sensing ion channels (ASICs) are a family of proton-sensing channels expressed throughout the nervous system. Their activity is linked to a variety of...

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Identifiers

PMID: 26589317
DOI: 10.1007/s12017-015-8380-8

Genes

ASIC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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