Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Activation of Type I and III Interferon Response by Mitochondrial and Peroxisomal MAVS and Inhibition by Hepatitis C Virus

20 Nov 2015

Abstract excerpt

Sensing viruses by pattern recognition receptors (PRR) triggers the innate immune system of the host cell and activates immune signaling cascades such as the RIG-I/IRF3 pathway. Mitochondrial antiviral-signaling protein (MAVS, also known as IPS-1, Cardif, and VISA) is the crucial adaptor protein of this pathway localized on mitochondria, peroxisomes and mitochondria-associated membranes of the endoplasmic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hepatitis C virus research
Share to interferon and immune responses
Share to Viral Infections and Immunology Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26588843
DOI: 10.1371/journal.ppat.1005264

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Activation of Type I and III Interferon Response by Mitochondrial and Peroxisomal MAVS and Inhibition by Hepatitis C VirusPMID 26588843Read ↗

Hepatitis C virus NS3-4A inhibits the peroxisomal MAVS-dependent antiviral signalling response.Semantic proximity Read ↗

Flavivirus Infection Impairs Peroxisome Biogenesis and Early Antiviral SignalingSemantic proximity Read ↗

Hepatitis E virus persists in the presence of a type III interferon responseSemantic proximity Read ↗

A conventional immune regulator mitochondrial antiviral signaling protein blocks hepatic steatosis by maintaining mitochondrial homeostasisSemantic proximity Read ↗

Pseudorabies virus infection triggers mitophagy to dampen the interferon response and promote viral replicationSemantic proximity Read ↗

Class A Scavenger Receptor 1 (MSR1) Restricts Hepatitis C Virus Replication by Mediating Toll-like Receptor 3 Recognition of Viral RNAs Produced in Neighboring CellsSemantic proximity Read ↗

MAVS-Mediated Apoptosis and Its Inhibition by Viral ProteinsSemantic proximity Read ↗

The MAVS Immune Recognition Pathway in Viral Infection and SepsisSemantic proximity Read ↗

Hepatitis A and Hepatitis C Viruses: Divergent Infection Outcomes Marked by Similarities in Induction and Evasion of Interferon ResponsesSemantic proximity Read ↗

The Hepatitis C Virus-Induced Membranous Web and Associated Nuclear Transport Machinery Limit Access of Pattern Recognition Receptors to Viral Replication SitesSemantic proximity Read ↗

Interplay between Zika Virus and Peroxisomes during InfectionSemantic proximity Read ↗

Viral and therapeutic control of IFN-beta promoter stimulator 1 during hepatitis C virus infection.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.