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Article

Interplay between Zika Virus and Peroxisomes during Infection

15 Jul 2019

Abstract excerpt

Zika virus (ZIKV) has emerged as an important human pathogen that can cause congenital defects in the fetus and neurological conditions in adults. The interferon (IFN) system has proven crucial in restricting ZIKV replication and pathogenesis. The canonical IFN response is triggered by the detection of viral RNA through RIG-I like receptors followed by activation of the adaptor protein MAVS on mitochondrial...

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PMID: 31311201
DOI: 10.3390/cells8070725

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