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Article

The MAVS Immune Recognition Pathway in Viral Infection and Sepsis

5 Aug 2021

Abstract excerpt

Significance: It is estimated that close to 50 million cases of sepsis result in over 11 million annual fatalities worldwide. The pathognomonic feature of sepsis is a dysregulated inflammatory response arising from viral, bacterial, or fungal infections. Immune recognition of pathogen-associated molecular patterns is a hallmark of the host immune defense to combat microbes and to prevent the progression to...

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PMID: 34348482
DOI: 10.1089/ars.2021.0167

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