Article
Automated Multiplex LC-MS/MS Assay for Quantifying Serum Apolipoproteins A-I, B, C-I, C-II, C-III, and E with Qualitative Apolipoprotein E Phenotyping.
Clinical chemistry - 1 Jan 2016
van den Broek Irene, Romijn Fred P H T M, Nouta Jan, van der Laarse Arnoud, Drijfhout Jan W, Smit Nico P M, van der Burgt Yuri E M, Cobbaert Christa M
Abstract excerpt
BACKGROUND: Direct and calculated measures of lipoprotein fractions for cardiovascular risk assessment suffer from analytical inaccuracy in certain dyslipidemic and pathological states, most commonly hypertriglyceridemia. LC-MS/MS has proven suitable for multiplexed quantification and phenotyping of apolipoproteins. We developed and provisionally validated an automated assay for quantification of apolipoprotein...
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