Article
Resolution of apolipoprotein A1 and A2 proteoforms: their cardiometabolic correlates and implications for future research
1 Aug 2022
Abstract excerpt
PURPOSE OF REVIEW: A 'proteoform' is defined as one specific protein structural form that results from the combination of allelic variation, alternative RNA splicing, and/or posttranslational modifications (PTMs) in specific locations on the amino acid backbone. Apolipoproteins A1 and A2 are highly abundant apolipoproteins that mediate HDL structure and function. ApoA1 and apoA2 are known to undergo PTMs, which...
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