Article
Cohort-based strategies as an in-house tool to evaluate and improve phenotyping robustness of LC-MS/MS lipidomics platforms.
Analytical and bioanalytical chemistry - 1 Oct 2024
Zöhrer Benedikt, Gómez Cristina, Jaumot Joaquim, Idborg Helena, Torekov Signe S, Wheelock Åsa M, Wheelock Craig E, Checa Antonio
Abstract excerpt
In recent years, instrumental improvements have enabled the spread of mass spectrometry-based lipidomics platforms in biomedical research. In mass spectrometry, the reliability of generated data varies for each compound, contingent on, among other factors, the availability of labeled internal standards. It is challenging to evaluate the data for lipids without specific labeled internal standards, especially when...
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