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Article

Sodium chloride promotes pro-inflammatory macrophage polarization thereby aggravating CNS autoimmunity.

Journal of autoimmunity - 1 Feb 2016

Hucke Stephanie, Eschborn Melanie, Liebmann Marie, Herold Martin, Freise Nicole, Engbers Annika, Ehling Petra, Meuth Sven G, Roth Johannes, Kuhlmann Tanja, Wiendl Heinz, Klotz Luisa

Abstract excerpt

The increasing incidence in Multiple Sclerosis (MS) during the last decades in industrialized countries might be linked to a change in dietary habits. Nowadays, enhanced salt content is an important characteristic of Western diet and increased dietary salt (NaCl) intake promotes pathogenic T cell responses contributing to central nervous system (CNS) autoimmunity. Given the importance of macrophage responses for...

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Share to Autoimmunity
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Encephalomyelitis, Autoimmune, Experimental

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Share to MAP Kinase Signaling System

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Source

Identifiers

PMID: 26584738
DOI: 10.1016/j.jaut.2015.11.001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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