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Article

The immune-modulatory role of apolipoprotein E with emphasis on multiple sclerosis and experimental autoimmune encephalomyelitis.

Clinical & developmental immunology - 1 Jan 2010

Zhang Hong-Liang, Wu Jiang, Zhu Jie

Abstract excerpt

Apolipoprotein E (apoE) is a 34.2 kDa glycoprotein characterized by its wide tissue distribution and multiple functions. The nonlipid-related properties of apoE include modulating inflammation and oxidation, suppressing T cell proliferation, regulating macrophage functions, and facilitating lipid antigen presentation by CD1 molecules to natural killer T (NKT) cells, and so forth. Increasing studies have revealed...

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Share to Apolipoproteins E
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Encephalomyelitis, Autoimmune, Experimental

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Share to Oxidation-Reduction

Share to Polymorphism, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 20613949
DOI: 10.1155/2010/186813
PMCID: PMC2896842

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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