Article
Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells.
Nature - 25 Apr 2013
Kleinewietfeld Markus, Manzel Arndt, Titze Jens, Kvakan Heda, Yosef Nir, Linker Ralf A, Muller Dominik N, Hafler David A
Abstract excerpt
There has been a marked increase in the incidence of autoimmune diseases in the past half-century. Although the underlying genetic basis of this class of diseases has recently been elucidated, implicating predominantly immune-response genes, changes in environmental factors must ultimately be driving this increase. The newly identified population of interleukin (IL)-17-producing CD4(+) helper T cells (TH17 cells)...
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