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Article

Patients with chronic hepatitis C express a high percentage of CD4(+)CXCR5(+) T follicular helper cells.

Journal of gastroenterology - 1 Sept 2012

Feng Junyan, Hu Xiaoli, Guo Hui, Sun Xiguang, Wang Juan, Xu Lijun, Jiang Zhenyu, Xu Bingchuan, Niu Junqi, Jiang Yanfang

Abstract excerpt

BACKGROUND: T follicular helper (T(FH)) cells are a subpopulation of T-helper cells which regulate humoral immune responses. The role of T(FH) cells in viral infection is unclear. This study examined the possible involvement of CD4(+)CXCR5(+) T(FH) cells in chronic hepatitis C (HCV) infection. METHODS: The percentages of peripheral blood CD4(+)CXCR5(+) T(FH) cells, inducible T-cell costimulator cells, and/or...

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Share to CD4-Positive T-Lymphocytes
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepatitis C, Chronic

Share to Inducible T-Cell Co-Stimulator Protein

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Share to Programmed Cell Death 1 Receptor

Share to T-Lymphocytes, Helper-Inducer

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Source

Identifiers

PMID: 22426636
DOI: 10.1007/s00535-012-0568-1

Genes

CXCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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